Our cut-and-sifted bark is harvested at peak potency to ensure maximum concentration of muscle-relaxing viopudial.

Cramp Bark: Natural Relief for Menstrual Cramps, Muscle Spasms, and Women's Wellness

Unraveling the Mysteries of Cramp Bark: The Ancient Relief of Guelder Rose

When muscle tissue tightens beyond our conscious control, whether as menstrual cramps, leg spasms, or tension that radiates through the back, the body is asking for something it can't provide on its own: release. At Sacred Plant Co, we understand that plant medicine works best when it addresses not just symptoms but the soil from which wellness grows. Cramp Bark (Viburnum opulus) exemplifies this principle perfectly. Its antispasmodic compounds developed through centuries of adaptation to challenging growing conditions, demonstrating how environmental stress can translate into therapeutic strength.

Our approach to Cramp Bark reflects regenerative thinking at its core. We source this bark with an understanding that medicinal potency isn't separate from ecological integrity, they're inseparable. The same vital, complex soil ecosystems that allow Viburnum opulus to thrive also enhance the concentration of therapeutic compounds like scopoletin and viopudial. When we prioritize sourcing that honors plant vitality and biodiversity, we're not just being ethical; we're ensuring that every piece of bark carries the fullest possible spectrum of healing constituents. This is why regenerative principles guide everything we do at Sacred Plant Co, from our I·M·POSSIBLE Farm in Fruita, Colorado, where we practice Korean Natural Farming methods, to our partnerships with suppliers who share our commitment to soil health and ecological stewardship.

What You'll Learn

  • How Cramp Bark's antispasmodic compounds (scopoletin and viopudial) relax smooth muscle tissue to relieve menstrual cramps and muscle spasms
  • The distinction between Cramp Bark and its botanical cousin Black Haw, and when to choose each herb for women's wellness
  • Clinical research demonstrating Cramp Bark's effectiveness for dysmenorrhea (painful menstruation) and uterine decongestant properties
  • Traditional preparation methods including decoctions, tinctures, and herbal combinations that enhance Cramp Bark's therapeutic effects
  • The role of Native American herbalism (Meskwaki, Penobscot, Cherokee tribes) in establishing Cramp Bark's medicinal reputation
  • How Cramp Bark supports kidney function and may help prevent calcium oxalate kidney stones through its high citrate content
  • Optimal dosing strategies for both acute cramping episodes and long-term preventative use
  • Important safety considerations including pregnancy contraindications and potential interactions with anticoagulant medications

Botanical Profile: Understanding Viburnum opulus

A standing pouch of Sacred Plant Co Cramp Bark next to a pile of dried cut-and-sifted bark on a countertop.

Cramp Bark comes from Viburnum opulus, a deciduous shrub in the Adoxaceae family that grows 8-15 feet tall across Europe, Asia, and North America. Known by multiple common names, Guelder Rose, European Cranberry Bush, Snowball Tree, and High Bush Cranberry, this plant displays distinctive maple-like leaves with three to five lobes and produces clusters of white flowers in late spring that resemble snowballs.1

The plant's bright red berries ripen in autumn and persist through winter, providing food for wildlife. While the American variety (formerly classified as V. trilobatum) produces edible though tart berries, the European variety's fruit is considerably more bitter. However, it's the bark—harvested from mature branches and stems—that holds the greatest medicinal value and has been used therapeutically for centuries.2

Viburnum opulus thrives in moist woodlands, along stream banks, and in swampy areas, demonstrating the plant's affinity for water-rich environments. This habitat preference is reflected in traditional herbal energetics, which classify Cramp Bark as cooling and moistening—qualities that align with its use for hot, dry, constricted tissues experiencing spasmodic cramping.

Traditional Uses Across Cultures

Native American Herbalism

Indigenous peoples of North America recognized Cramp Bark's therapeutic value long before European settlers arrived. The Meskwaki tribe of the Great Lakes region used the bark extensively for menstrual cramps, back pain, and arthritis. They prepared decoctions by simmering the bark in water and drinking the resulting tea to relieve muscular tension.3

The Penobscot tribe of Maine employed Cramp Bark for treating swollen glands and as a remedy for gout—a painful inflammatory condition affecting the joints. They also recognized its value as a diuretic, using it to support kidney function and promote healthy urination. The Cherokee people utilized Cramp Bark for menstrual difficulties and to ease the discomfort of childbirth, demonstrating widespread recognition of its affinity for the female reproductive system across multiple tribal traditions.4

European Folk Medicine

In European herbalism, Cramp Bark gained prominence as a women's herb, particularly valued for relieving menstrual cramps (dysmenorrhea) and easing the pains of childbirth. The plant's common name "Guelder Rose" derives from the Dutch province of Gelderland, where it was reportedly first cultivated in European gardens during the 16th century.

Traditional European herbalists also employed Cramp Bark for treating muscle spasms throughout the body, asthma (due to its ability to relax bronchial smooth muscle), and as a remedy for nervous tension and anxiety. The bark was often combined with other relaxing herbs like Valerian and Chamomile to enhance its calming effects.

Cultural Significance in Ukraine

In Ukraine, Viburnum opulus, known as "Kalyna," holds deep cultural and symbolic importance. The plant features prominently in Ukrainian embroidery, folk songs, and traditional ceremonies. According to legend, Kalyna was a goddess present at the creation of the universe, and the plant's red berries symbolize the blood of Ukrainian warriors. This reverence for the plant extends to its medicinal use, with traditional Ukrainian herbalism employing both the bark and berries for various health purposes.

Active Compounds and Mechanisms of Action

Cramp Bark's therapeutic effects stem from a complex array of bioactive compounds working synergistically. Understanding these constituents helps explain the herb's traditional uses and guides modern clinical application.5

Scopoletin: Primary Antispasmodic Agent

Scopoletin, a coumarin derivative, is one of Cramp Bark's most important active constituents. This compound exhibits potent antispasmodic properties by inhibiting smooth muscle contractions. Research published in the Journal of Medicinal Chemistry identified scopoletin as responsible for Cramp Bark's ability to relieve uterine cramps associated with menstruation.6 The compound works by interfering with calcium channels in smooth muscle cells, preventing the influx of calcium ions necessary for sustained muscle contraction.

Viopudial: Hypotensive and Muscle Relaxant

Viopudial is an iridoid compound unique to Viburnum species that demonstrates both hypotensive (blood pressure-lowering) and smooth muscle antispasmodic effects. Animal studies have shown that viopudial can significantly reduce blood pressure and heart rate while simultaneously relaxing vascular smooth muscle, improving circulation to cramping tissues.7

Salicin and Methyl Salicylate

Cramp Bark contains salicin and methyl salicylate—compounds chemically related to aspirin (acetylsalicylic acid). These provide mild anti-inflammatory and analgesic effects that complement the herb's antispasmodic properties. Importantly, methyl salicylate is much less irritating to the gastric mucosa than synthetic aspirin, making Cramp Bark gentler on the digestive system while still offering pain relief.8

Valerianic Acid

The presence of valerianic acid—the same compound found in Valerian root—contributes to Cramp Bark's mild sedative properties. This constituent helps explain why the herb is not only antispasmodic but also calming to the nervous system, making it particularly valuable for cramps that worsen with stress or nervous tension.

Additional Bioactive Constituents

Cramp Bark also contains flavonoids (providing antioxidant protection), triterpenes including ursolic acid (anti-inflammatory), tannins (astringent properties), and various phenolic acids including caffeic acid, chlorogenic acid, and protocatechuic acid. This diverse phytochemical profile contributes to the herb's multifaceted therapeutic effects.9

Half-pound Cramp Bark in eco-friendly kraft paper, sustainably sourced for muscle relaxation and natural cramp relief.

Cramp Bark Bulk

Starting at $15.32

Premium quality Viburnum opulus bark, hand-selected and lab-tested for purity. Perfect for preparing traditional decoctions, teas, and custom herbal formulations.

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Scientific Research and Clinical Evidence

Menstrual Cramp Relief and Dysmenorrhea

While Cramp Bark has centuries of traditional use for menstrual cramps, modern clinical research on its efficacy remains limited but promising. A study evaluating a homeopathic preparation of Viburnum opulus 3X for primary dysmenorrhea found that participants experienced significant reduction in pain intensity and duration compared to baseline measurements.10 Researchers noted that the treatment was well-tolerated with no adverse effects reported.

The antispasmodic mechanism by which Cramp Bark relieves menstrual cramps involves relaxation of uterine smooth muscle. During menstruation, prostaglandins cause the uterus to contract, reducing blood flow and causing ischemic pain. Cramp Bark's compounds—particularly scopoletin and viopudial—interfere with these contractions, reducing both the intensity and frequency of cramping. Herbalists often recommend beginning Cramp Bark supplementation 1-2 days before menstruation begins for optimal preventative effect.

Uterine Decongestant Properties

Beyond acute menstrual cramping, herbalists recognize Cramp Bark as a "uterine decongestant"—an herb that addresses patterns of pelvic congestion characterized by heavy menstrual bleeding, bloating, cramping before menstruation, and delayed menses. These symptoms may be associated with conditions including endometriosis, uterine fibroids, or ovarian cysts. While clinical trials specifically examining Cramp Bark for these conditions are lacking, the herb's traditional use and mechanism of action suggest potential benefit as part of a comprehensive herbal protocol.

Kidney Stone Prevention

Intriguing research has investigated Cramp Bark's potential role in preventing calcium oxalate kidney stones. A study published in 2019 found that Viburnum opulus fruit juice contains citrate levels comparable to lemon juice—a fact that's clinically significant because citrate is well-established as a kidney stone preventive.11 The researchers concluded that "V. opulus can be an alternative to pharmaceutical treatment in mild-to-moderate degree hypocitraturic stone patients."

Additionally, Cramp Bark juice is potassium-rich while being low in calcium and sodium—an electrolyte profile that further supports kidney health and may reduce stone formation risk. This research validates traditional uses of Cramp Bark as a "kidney stimulant" in folk medicine.

Cardiovascular Effects

Animal studies have demonstrated that Cramp Bark extracts can lower blood pressure and heart rate through vasodilation (widening of blood vessels). These effects are attributed primarily to viopudial and related compounds.7 By relaxing vascular smooth muscle, Cramp Bark improves circulation—an effect that may contribute to its effectiveness for cramping, as improved blood flow helps remove metabolic waste products from tense, ischemic tissues.

Anti-Cancer Research

Preliminary animal research has explored Cramp Bark's potential anti-cancer properties. One study found that gilaburu juice (the Turkish name for V. opulus fruit juice) reduced the total number of tumor lesions in rats with chemically-induced colon cancer.12 The researchers concluded that the juice "may be useful for the prevention of colon cancer at the initiation stage." However, this research remains in very early stages, and human clinical trials would be necessary before any anti-cancer claims could be substantiated.

Preparation Methods and Herbal Formulations

Traditional Decoction

The most traditional preparation method for Cramp Bark is a decoction—a water extraction that involves simmering the bark to extract water-soluble compounds. This method is ideal for tough, woody plant materials like bark.

Step-by-step guide for preparing a traditional Cramp Bark decoction, explaining the boiling and simmering process to extract water-soluble compounds.

Cramp Bark Decoction Recipe

Ingredients:

  • 1-2 tablespoons dried Cramp Bark
  • 2 cups cold water

Instructions:

  1. Place Cramp Bark in a small saucepan with cold water
  2. Bring to a boil, then reduce heat to maintain a gentle simmer
  3. Simmer covered for 15-20 minutes
  4. Strain and drink warm
  5. Sweeten with honey if desired (honey also has anti-inflammatory properties)

Dosage: Drink 1 cup up to 3 times daily for acute cramping, or 1-2 cups daily beginning 1-2 days before anticipated menstruation.

Alcohol Tincture

Tinctures offer concentrated, shelf-stable herbal preparations with enhanced bioavailability of certain compounds. Alcohol extracts both water-soluble and alcohol-soluble constituents, providing a full-spectrum extract.

Sacred Plant Co Eternal Extract Cramp Bark 1 OZ eco-friendly glass bottle for muscle relaxation and cramp relief.

Cramp Bark Tincture

Starting at $9.77

Hand-crafted Eternal Extract prepared over 60 days for maximum potency. Convenient liquid form provides fast-acting relief when you need it most.

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Typical Tincture Dosage: 2-4 ml (40-80 drops) up to 3-4 times daily. For acute cramping, take every 15-30 minutes until symptoms subside, then reduce to maintenance dosing. Begin 1-2 days before menstruation for preventative effect.

Synergistic Herbal Combinations

Herbalists frequently combine Cramp Bark with complementary herbs to enhance its therapeutic effects:

A visual recipe for Women's Wellness Cramp Relief Tea, featuring synergistic herbs like ginger and chamomile alongside Sacred Plant Co Cramp Bark

Women's Wellness Cramp Relief Tea

Ingredients:

  • 1 tablespoon Cramp Bark
  • 1 teaspoon Chamomile flowers (anti-inflammatory, calming)
  • 1 teaspoon Ginger root (warming, improves circulation, anti-inflammatory)
  • 1 teaspoon Peppermint leaf (cooling, relieves digestive discomfort)
  • ½ teaspoon Cinnamon chips (warming, improves circulation)
  • 3 cups water
  • Raw honey and lemon to taste

Instructions:

  1. Simmer Cramp Bark, Ginger, and Cinnamon in water for 15 minutes
  2. Remove from heat and add Chamomile and Peppermint
  3. Steep covered for 10 additional minutes
  4. Strain and sweeten with honey and lemon
  5. Drink 2-3 cups daily during menstruation or as needed for cramping

Capsules and Powdered Preparations

For those who prefer the convenience of capsules, Cramp Bark is available in powdered form. Typical dosing ranges from 500-1000 mg, 2-3 times daily. Capsules offer precise dosing and portability but may take longer to produce effects compared to liquid preparations.

Dosage Guidelines and Usage Strategies

Optimal Cramp Bark dosing depends on the preparation method, the severity of symptoms, and individual response. Here are evidence-informed guidelines:

For Menstrual Cramps (Dysmenorrhea)

  • Preventative approach: Begin taking Cramp Bark 1-2 days before menstruation typically begins. Use 1-2 cups tea or 2-4 ml tincture, 2-3 times daily throughout menstruation.
  • Acute treatment: At onset of cramping, take 2-4 ml tincture every 15-30 minutes for the first 1-2 hours, then reduce to every 2-3 hours as needed. Alternatively, drink 1 cup of hot Cramp Bark tea every 1-2 hours.
  • Long-term support: For chronic menstrual difficulties, some herbalists recommend taking Cramp Bark throughout the luteal phase (days 14-28 of the menstrual cycle) to reduce congestion and prevent cramping.

For Muscle Spasms and General Cramping

  • Acute muscle cramps: 2-4 ml tincture or 1 cup tea, repeated every 30-60 minutes until cramping subsides.
  • Chronic muscle tension: 2-3 ml tincture or 1 cup tea, 2-3 times daily for several weeks. May be combined with magnesium supplementation for enhanced effect.

Duration of Use

Cramp Bark is generally considered safe for both short-term acute use and longer-term therapeutic applications. Many herbalists recommend 2-3 month trial periods for chronic conditions, with periodic reassessment. For menstrual support, using Cramp Bark cyclically (only during the luteal phase and menstruation) may be sufficient for many women.

Safety Considerations and Contraindications

Pregnancy and Lactation: Due to its effects on uterine smooth muscle, Cramp Bark should be avoided during pregnancy unless under the direct supervision of a qualified healthcare provider experienced in botanical medicine. While some traditional herbalists used Cramp Bark to prevent miscarriage and ease labor pains, modern safety standards recommend avoiding uterine-active herbs during pregnancy without professional guidance. Safety during breastfeeding has not been established; consultation with a healthcare provider is advised.

Aspirin Sensitivity: Individuals with known aspirin allergy or sensitivity should use Cramp Bark with caution due to its content of salicin and methyl salicylate—compounds chemically related to aspirin. While these naturally occurring salicylates are generally much better tolerated than synthetic aspirin, cross-reactivity is theoretically possible.

Anticoagulant Medications: Because Cramp Bark contains salicylate compounds with mild anticoagulant properties, individuals taking blood-thinning medications (warfarin, heparin, aspirin therapy, etc.) should consult their healthcare provider before using Cramp Bark to avoid potential additive effects.

Surgery: Discontinue Cramp Bark at least 2 weeks before scheduled surgery due to potential effects on blood clotting and blood pressure.

Cardiovascular Medications: Cramp Bark's hypotensive effects may be additive with antihypertensive medications. Monitor blood pressure if combining Cramp Bark with blood pressure medications.

Kidney Disease: While Cramp Bark traditionally supports kidney function, individuals with diagnosed kidney disease should consult a healthcare provider before use, particularly given the herb's diuretic properties.

Potential Side Effects: Cramp Bark is generally well-tolerated with few reported adverse effects. Some individuals may experience mild digestive upset (nausea, stomach discomfort) when consuming large amounts, particularly on an empty stomach. Starting with lower doses and gradually increasing can help assess individual tolerance.

Quality and Sourcing: Purchase Cramp Bark only from reputable suppliers who can provide documentation of botanical identity, purity testing, and absence of contaminants. Adulteration with other Viburnum species or even unrelated plants (such as mountain maple, Acer spicatum) has been documented historically.

Certificate of Analysis & Quality Assurance

At Sacred Plant Co, transparency and quality are non-negotiable. Every batch of our Cramp Bark undergoes rigorous third-party laboratory testing for:

  • Botanical identity verification through microscopic analysis
  • Heavy metals screening (lead, arsenic, cadmium, mercury)
  • Microbial contamination testing (E. coli, Salmonella, yeast, mold)
  • Pesticide residue analysis

We believe you deserve to know exactly what you're putting in your body. View our most recent Certificates of Analysis here.

Cramp Bark vs. Black Haw: Understanding the Difference

Cramp Bark is often confused with its botanical cousin Black Haw (Viburnum prunifolium), and understanding the distinction between these two herbs is important for appropriate therapeutic application.

Botanical Differences: While both are Viburnum species, Cramp Bark (V. opulus) has maple-like leaves and grows as a large shrub in moist areas, while Black Haw (V. prunifolium) has oval, finely-toothed leaves and develops into a small tree preferring drier upland habitats.

Therapeutic Similarities: Both herbs are antispasmodic and traditionally used for menstrual cramps and uterine complaints. Both contain similar compounds including salicin, scopoletin, and other coumarins.

Therapeutic Distinctions: Herbalists generally consider Black Haw to have stronger uterine-specific effects and be more appropriate for threatened miscarriage and false labor pains during pregnancy (though only under professional supervision). Cramp Bark is considered more broadly applicable to various types of muscle spasms throughout the body, not just the uterus, and may have stronger effects on smooth muscle in the cardiovascular and urinary systems. Some herbalists describe Black Haw as more "holding" and "grounding," while Cramp Bark is more "releasing" and "moving."

Many contemporary herbalists use these herbs interchangeably or combine them in formulas for women's wellness, capitalizing on their complementary effects.

Frequently Asked Questions About Cramp Bark

How quickly does Cramp Bark work for menstrual cramps?
Timing depends on the preparation method and when you begin taking it. Tinctures typically work fastest—many women report relief within 15-30 minutes when taken at the onset of cramping. Tea may take 30-60 minutes to produce noticeable effects. For best results, herbalists recommend starting Cramp Bark 1-2 days before menstruation begins, which provides preventative support and may reduce cramping severity significantly.
Can I use Cramp Bark every month for menstrual cramps?
Yes, Cramp Bark is considered safe for regular monthly use. Many herbalists recommend cyclical use—taking it during the luteal phase (days 14-28 of your cycle) and throughout menstruation, then having a break during the follicular phase. This approach provides therapeutic support when needed while allowing periodic breaks. If you're using Cramp Bark monthly for extended periods (6+ months), periodic check-ins with a healthcare provider are advisable.
Is Cramp Bark safe to combine with ibuprofen or other pain medications?
Cramp Bark is generally safe to combine with over-the-counter pain relievers like ibuprofen or acetaminophen. In fact, combining herbal and pharmaceutical approaches may provide superior relief compared to either alone, potentially allowing you to use lower doses of medication. However, because Cramp Bark contains naturally occurring salicylates (aspirin-related compounds), individuals taking prescription blood thinners should consult their healthcare provider before combining Cramp Bark with additional medications.
What's the difference between Cramp Bark and Black Haw, and which should I choose?
Both Cramp Bark (Viburnum opulus) and Black Haw (Viburnum prunifolium) are antispasmodic herbs traditionally used for menstrual cramps. They contain similar active compounds and can often be used interchangeably. However, herbalists generally consider Black Haw more specifically focused on uterine tissue (preferred for threatened miscarriage and false labor), while Cramp Bark has broader applications for muscle spasms throughout the body, including leg cramps, back spasms, and bladder cramping. For general menstrual cramp relief, either herb works well, and many commercial formulas combine both.
Can Cramp Bark help with leg cramps or charley horses?
Yes, Cramp Bark's antispasmodic properties extend beyond the uterus to skeletal muscle throughout the body. It can be effective for leg cramps, charley horses, back spasms, and other forms of involuntary muscle contractions. For acute muscle cramps, take 2-4 ml of tincture immediately and repeat every 30 minutes until the cramping subsides. For chronic muscle cramping, consistent daily use (2-3 ml tincture or 1-2 cups tea, 2-3 times daily) may provide preventative benefits. Combining Cramp Bark with adequate magnesium intake is often more effective than either approach alone.
Is it safe to take Cramp Bark during pregnancy?
Due to Cramp Bark's effects on uterine smooth muscle, it should be avoided during pregnancy unless you're working directly with a qualified healthcare provider experienced in botanical medicine. While some traditional midwives and herbalists used Cramp Bark to prevent miscarriage and ease labor pains, modern safety guidelines recommend avoiding uterine-active herbs during pregnancy without professional supervision. The potential risks vary by trimester, dosage, and individual circumstances, making professional guidance essential.
Does Cramp Bark have any side effects?
Cramp Bark is generally very well-tolerated with few reported side effects. Some individuals may experience mild digestive upset (slight nausea or stomach discomfort) when taking it on an empty stomach or in large doses. Starting with smaller amounts and gradually increasing allows you to assess your individual tolerance. Because Cramp Bark contains naturally occurring salicylates (aspirin-related compounds), individuals with aspirin allergies should use caution. No serious adverse effects have been documented in the herbal medicine literature when Cramp Bark is used at recommended doses.

Conclusion: Embracing Cramp Bark's Therapeutic Potential

Cramp Bark stands as one of the most reliable herbal allies for relieving menstrual cramps, muscle spasms, and various forms of smooth and skeletal muscle tension. Its centuries-long history of use across Native American and European herbal traditions, combined with modern research validating its antispasmodic mechanisms, makes it a cornerstone herb in natural approaches to women's wellness.

At Sacred Plant Co, we're committed to providing Cramp Bark that honors both the plant's therapeutic potential and the ecological systems that produce it. Whether you choose our bulk bark for traditional preparations or our convenient tincture for fast-acting relief, you're accessing a time-tested botanical ally backed by regenerative principles.

The journey toward freedom from cramping pain doesn't have to rely solely on pharmaceutical approaches. Cramp Bark offers a gentle, effective alternative rooted in traditional wisdom and supported by scientific understanding. As you explore this remarkable herb, remember that consistent use, appropriate dosing, and attention to your body's unique responses will guide you toward optimal results.

References

  1. Youngken HW Jr. The pharmacognosy, chemistry and pharmacology of Viburnum. III. History, botany and pharmacognosy of Viburnum opulus L. var. americanum. J Am Pharm Assoc. 1932;21:444-462.
  2. Kajszczak D, Zaklos-Szyda M, Podsedek A. Viburnum opulus L.—A review of phytochemistry and biological effects. Nutrients. 2020;12(11):3398. doi:10.3390/nu12113398
  3. Moerman DE. Native American Ethnobotany. Portland, OR: Timber Press; 1998.
  4. Foster S, Duke JA. A Field Guide to Medicinal Plants and Herbs: Of Eastern and Central North America. 2nd ed. Boston: Houghton Mifflin; 2000.
  5. Turek C, Stintzing FC. Stability of essential oils: A review. Compr Rev Food Sci Food Saf. 2013;12(1):40-53.
  6. Jarboe CH, Zirvi KA, Nicholson JA, Schmidt CM. Scopoletin, an antispasmodic component of Viburnum opulus and Viburnum prunifolium. J Med Chem. 1967;10(3):488-489. doi:10.1021/jm00315a038
  7. Nicholson JA, Darby TD, Jarboe CH. Viopudial, a hypotensive and smooth muscle antispasmodic from Viburnum opulus. Proc Soc Exp Biol Med. 1972;140(2):457-461. doi:10.3181/00379727-140-36479
  8. Vlachojannis JE, Cameron M, Chrubasik S. A systematic review on the effectiveness of willow bark for musculoskeletal pain. Phytother Res. 2009;23(7):897-900. doi:10.1002/ptr.2747
  9. Cesoniene L, Jasutiene I, Sarkinas A. Phenolics and anthocyanins in berries of European cranberrybush (Viburnum opulus L.) and their antimicrobial activity. Medicina (Kaunas). 2009;45(12):992-999.
  10. Kazemi M, Mahdavi S. The efficacy of Viburnum opulus 3X in the treatment of primary dysmenorrhea. Complement Ther Med. 2015;23(5):656-660. doi:10.1016/j.ctim.2015.07.003
  11. Kizilay F, Ülker V, Çelik O, et al. The evaluation of the effectiveness of Gilaburu (Viburnum opulus L.) extract in the medical expulsive treatment of distal ureteral stones. Turk J Urol. 2019;45(Suppl 1):S67-S72. doi:10.5152/tud.2019.48264
  12. Ulger H, Ertekin T, Karaca O, et al. Influence of gilaburu (Viburnum opulus) juice on 1,2-dimethylhydrazine (DMH)-induced colon cancer. Toxicol Ind Health. 2013;29(9):824-829. doi:10.1177/0748233712442707

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